High-frequency oscillation in early adult respiratory distress syndrome

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High-frequency oscillation in early adult respiratory distress syndrome

Methods Objective: The aim of the study was to compare HFOV with a conventional ventilation strategy that used low tidal volumes and high levels of positive end-expiratory pressure in patients with new-onset, early (<72 hours) moderate to severe ARDS. Design: A multicenter, randomized, controlled trial was conducted in 39 ICUs in five countries. Setting: Participants were adults with new-onset,...

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High-frequency oscillation in early acute respiratory distress syndrome.

BACKGROUND Previous trials suggesting that high-frequency oscillatory ventilation (HFOV) reduced mortality among adults with the acute respiratory distress syndrome (ARDS) were limited by the use of outdated comparator ventilation strategies and small sample sizes. METHODS In a multicenter, randomized, controlled trial conducted at 39 intensive care units in five countries, we randomly assign...

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Haemodynamic changes during high frequency oscillation for respiratory distress syndrome.

In a crossover trial left ventricular output (LVO), cerebral blood flow velocity (CBFV), and resistance index (RI) of the anterior cerebral artery were compared using Doppler ultrasonography, in eight preterm infants with respiratory distress syndrome (RDS) during conventional mechanical ventilation and high frequency oscillation. LVO was 14% to 18% lower with high frequency oscillation. There ...

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Editorial II: High-frequency oscillation in acute respiratory distress syndrome (ARDS).

Over the past 15 years, the mortality associated with acute respiratory distress syndrome (ARDS) has steadily declined. In the late 1980s and early 1990s, 33% of patients with the syndrome survived to leave hospital, compared with survival rates of 60–75% reported more recently. Although the explanation for this reduction is likely to be multifactorial, improvements in ventilation techniques ha...

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Prospective trial of high-frequency oscillation in adults with acute respiratory distress syndrome.

OBJECTIVE To evaluate the safety and efficacy of high-frequency oscillatory ventilation (HFOV) in adult patients with the acute respiratory distress syndrome (ARDS) and oxygenation failure. DESIGN Prospective, clinical study. SETTING Intensive care and burn units of two university teaching hospitals. PATIENTS Twenty-four adults (10 females, 14 males, aged 48.5 +/- 15.2 yrs, Acute Physiolo...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2014

ISSN: 1364-8535

DOI: 10.1186/cc13919